Milwaukee travels to Wrigley Field for a day-night doubleheader against Chicago, a marquee tilt in which the Brewers (78-45) look to extend their NL Central lead behind Freddy Peralta and a strong Milwaukee rotation. Cade Horton, a Cubs rookie, gets the ball in the opener as Chicago (70-53) tries to swing a critical series back in their direction eight games out in the division race.

Chicago wore yesterday’s 4-3 win over the Pirates as a springboard, with Dansby Swanson driving in the decisive run and Pete Crow-Armstrong heating up after an August drought, amassing five hits over the weekend. Milwaukee’s side saw the Reds end a 14-game win streak, but Jose Quintana offered another quality start that kept the Brewers in the top tier of the league. The clash features a high-upside fantasy matchup: Peralta’s elite strikeout upside vs Horton’s rookie upside, with Yelich riding an August hot streak for Milwaukee and Crow-Armstrong threatening Cubs outfield upside.

Rotoworld’s betting framework leans toward a high-scoring affair given line details (over/under near 8) and bullpen leverage, though the model treads carefully on the moneyline for a Brewers tilt. For fantasy managers, the brewing narratives center on Peralta’s strikeout pace, Horton’s rookie ceiling, Yelich’s August surge, and the Cubs’ emerging outfield momentum from Crow-Armstrong, all of which could shape daily lineups and waiver decisions this slate.

Cincinnati Reds defeated Milwaukee Brewers 3-2 in 10 innings, snapping Milwaukee’s franchise-record 14-game win streak. Austin Hays delivered a bases-loaded RBI single to cap a 10th-inning rally after Spencer Steer’s bunt move and two intentional walks loaded the bases. Will Benson reached on a fielding error that tied the game earlier, and Jose Trevino added the eventual game-winner. Graham Ashcraft earned the win after a quality start from Andrew Abbott; Emilio Pagán took the loss. The Reds have now avoided being swept in 40 straight series, the longest streak in franchise history. Up next: Freddy Peralta starts for Milwaukee against the Cubs; Brady Singer will start for Cincinnati against the Angels.

Cincinnati Reds toppled Milwaukee in a dramatic 3-2 walk-off in 10 innings to snap the Brewers’ 14-game win streak, the longest active streak in MLB this season. Andrew Abbott worked seven scoreless frames for Cincinnati, while Milwaukee’s offense went quiet until a ninth-inning rally was sparked by William Contreras’ two-run homer that flipped a tight game in the Brewers’ favor before Cincinnati answered late.

The bottom of the ninth produced an unearned Reds run to force extras, and in the 10th, Cincinnati loaded the bases after walking Elly De La Cruz and Will Benson. Austin Hays lined a walk-off single down the third-base line for the Reds, sealing a memorable comeback. Earlier, Blake Perkins’ bunt with the automatic runner on second backfired, ending Milwaukee’s late threat as the Reds finally closed it out in the extra inning.

Week 21 of 2025 brings a compact set of starting-pitcher waiver options, tailored for shallow leagues but with deeper-leaning plays that could pay off in standard formats. Will Warren anchors the top tier, offering reliable volume and recent five-inning quality starts as the Yankees chase wins. Jose Quintana stabilizes the rotation with dependable innings and solid ratios on a strong Brewers squad. Jose Soriano combines strikeouts with groundball variety for a back-end slot in many leagues. Hurston Waldrep offers upside as a top Braves prospect getting a late-season shot, while Charlie Morton provides veteran savvy as Detroit managers lean on experience. In deeper formats, Cristian Javier returns to form with injury-recovery potential; Zebby Matthews brings swing-and-mmiss upside tempered by HR risk; Nolan McLean, Jason Alexander, and Ryan Bergert each offer speculative, weekend-ready options with varying ceilings. Kyle Bradish, Michael McGreevy, Sean Burke, Michael Lorenzen, and Joey Wentz close the list with a mix of floor, wins potential, and breakout vibes. Proactive rosters can maximize Week 21 by pairing safe floors with high-upside stashes, while tracking BvP and PvB data for favorable matchups.

Milwaukee’s 14th straight win buried Cincinnati 6-3 in extras, a historic run paced by a late-game surge and a pinch-hit three-run blast from Andruw Monasterio. The Brewers sit 78-44 and own baseball’s best record, riding a wave of opportunistic offense and errant Reds defense that kept Milwaukee in striking distance all night. The Reds committed several costly miscues that fed Milwaukee’s progress, including a ninth-inning error that sparked a run and a misplayed bunt in extra innings that extended the frame.

Milwaukee’s late inning theatrics began with a 10th-inning rally sparked by Contreras’s leadoff single, then a sequence of Reds’ miscues and a decisive Monasterio homer that turned the tide. Noelvi Marte answered with a solo shot in the 11th, but Monasterio’s pinch-hit clout sealed a history-making win. Jose Quintana is lined up to face Andrew Abbott in the finale, with Milwaukee aiming for a 15th straight win Sunday against Cincinnati.